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Daybue(Trofinetide)
Daybue(Trofinetide)
- Medicine Name: Daybue
- Generic Name: Trofinetide
- Dosage Form & Strength: Oral Solution – 200 mg/mL
- Manufactured By: Acadia Pharmaceuticals Inc.
Daybue is a prescription oral therapy used for the treatment of Rett syndrome in adults and pediatric patients aged 2 years and older.
Recommended Dosage:
- Administer twice daily, in the morning and evening
- Can be taken with or without food
- Administered orally or through a G-tube (use G-port for GJ-tubes)
Weight-Based Dosing:
- 9–<12 kg: 5,000 mg (25 mL) twice daily
- 12–<20 kg: 6,000 mg (30 mL) twice daily
- 20–<35 kg: 8,000 mg (40 mL) twice daily
- 35–<50 kg: 10,000 mg (50 mL) twice daily
- ≥50 kg: 12,000 mg (60 mL) twice daily
- Diarrhea: Most patients may experience diarrhea. Cease laxatives before starting Daybue. Treat with antidiarrheals, hydrate, and monitor symptoms. Adjust or discontinue dosage if severe.
- Weight Loss: Monitor weight regularly. Interrupt or reduce dose if significant weight loss is observed.
- Common Adverse Reactions: Diarrhea and vomiting are the most frequently reported side effects.
Drug Interactions:
- Monitor for interactions with CYP3A4-sensitive substrates
- Avoid concurrent use with OATP1B1 and OATP1B3 substrates that may cause toxicity with altered plasma concentration
Required Documents for Import to India:
- Doctor’s valid prescription
- Diagnostic report confirming Rett syndrome
- Government-issued ID of the patient
Availability in India:
Daybue is a prescription-only medication and can be imported under India’s Named Patient Program through Global Rare Meds for individual patient use.
📧 info@globalraremeds.com
📞 +91-99675 15602 (Call/WhatsApp)
Global Rare Meds facilitates the legal import of Daybue (Trofinetide) through trusted international sources. All medication is processed through our licensed fulfillment center in Ambernath, Thane District, ensuring:
- Verified sourcing from FDA-approved manufacturers
- Proper handling and temperature-controlled shipping if needed
- Safe, compliant, and timely delivery directly to patients or hospitals
Q: What is Daybue® used for?
A: Daybue is approved for the treatment of Rett syndrome in patients aged 2 and above.
Q: What is the generic name of Daybue®?
A: Trofinetide
Q: How does Daybue® work?
A: Trofinetide is a synthetic analogue of IGF-1’s N-terminal tripeptide. It is believed to reduce neuroinflammation and support synaptic function, targeting core Rett syndrome symptoms.
Q: Is Daybue® FDA-approved?
A: Yes. The FDA approved Daybue in 2023 as the first treatment specifically for Rett syndrome.
Q: How is Daybue® administered?
A: It is an oral solution taken twice daily. It may also be administered via a G-tube if required.
Q: What are the common side effects of Daybue®?
A: Diarrhea, vomiting, and potential weight loss.
Q: What is the price of Daybue® in India?
A: Pricing may vary based on source and location. For the latest cost, contact info@globalraremeds.com or +91-99675 15602.
Q: Can I legally purchase Daybue® online in India?
A: Yes, Global Rare Meds supports legal import of Daybue for eligible patients through valid prescriptions and regulatory compliance.
Contact Patient Support
If you have questions about your order, need assistance with documentation, or require support with medicine availability, our GlobalRareMeds Patient Support Team is here to help. We aim to respond within 24 hours, Monday to Friday, between 9:00 AM and 10:00 AM IST.
info@globalraremeds.com
Phone
+91 99675 15602
+91 99675 15602
Disclaimer
All trademarks, brands, and product names featured on this website are the property of their respective owners. GlobalRareMeds does not claim ownership or affiliation unless explicitly stated. Our role is to provide reliable and transparent access to difficult-to-source medicines through named-patient import services, based on valid prescriptions and legal requirements.
The product-related content on this website is shared to the best of our knowledge, compiled from publicly available sources and regulatory documents. However, GlobalRareMeds does not guarantee the accuracy, completeness, or timeliness of this information. We strongly recommend that all medical decisions, including usage and dosage, be made only in consultation with the prescribing doctor. GlobalRareMeds assumes no responsibility for consequences arising from reliance on this information without appropriate medical guidance
