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Livmarli (Maralixibat)
Livmarli (Maralixibat)
- Medicine Name: Livmarli
- Generic Name: Maralixibat
- Dosage Form & Strength: Oral Solution – 9.5 mg/mL
- Manufactured By: Mirum Pharmaceuticals, Inc.
Livmarli is an FDA-approved IBAT inhibitor used for the treatment of cholestatic pruritus (itching) in individuals diagnosed with Alagille Syndrome (ALGS), aged 12 months and older.
This rare liver disorder often leads to persistent itching due to bile acid buildup. Livmarli significantly reduces this symptom, improving quality of life for pediatric patients.
Recommended Dosage:
- Start with 190 mcg/kg orally once daily, 30 minutes before the first meal
- After 1 week, increase to 380 mcg/kg once daily, as tolerated
- For patients over 70 kg, the maximum daily dose is 3 mL (28.5 mg)
- If taken with bile acid-binding resins, maintain a 4-hour gap between medications
- If a dose is missed and remembered within 12 hours, take it immediately; otherwise, skip the missed dose
Liver Monitoring: Conduct liver function tests before and during treatment. Interrupt or discontinue Livmarli if liver enzyme abnormalities persist or worsen.
Gastrointestinal Side Effects: Vomiting, diarrhea, and abdominal pain are common. Monitor hydration and consider dose adjustments if needed.
Vitamin Deficiency: Livmarli may interfere with the absorption of fat-soluble vitamins (A, D, E, K). Monitor levels regularly and supplement as required.
Not studied in cirrhotic ALGS patients – use caution.
To legally import Livmarli to India, the following documents are required:
- A valid prescription from a licensed medical practitioner
- Diagnostic reports confirming ALGS
- Government-issued ID proof of the patient
Livmarli is available in India through Named Patient Import facilitated by Global Rare Meds. The medication can be delivered in cities such as Mumbai, Delhi, Bangalore, Pune, Chennai, Hyderabad, Kolkata, Ahmedabad, and others.
📧 info@globalraremeds.com
📞 +91-99675 15602 (Call/WhatsApp)
Global Rare Meds sources Livmarli (Maralixibat) from certified suppliers in the USA, Europe, and Canada. All prescriptions are verified by pharmacists and dispatched from our licensed fulfillment center in Ambernath, Thane District.
We ensure:
- Regulatory compliance
- Cold chain logistics
- Secure packaging & nationwide delivery
- Support for international shipping where legally allowed
Q: What is Livmarli used for?
A: Livmarli is used to treat chronic itching caused by Alagille Syndrome in children aged 12 months and older.
Q: What is the generic name of Livmarli®?
A: Maralixibat
Q: Is Livmarli® FDA-approved?
A: Yes, approved on September 29, 2021.
Q: Who manufactures Livmarli®?
A: Mirum Pharmaceuticals, Inc.
Q: How is Livmarli taken?
A: As an oral solution, once daily before the first meal. Dose is based on body weight.
Q: What are the most common side effects?
A:
- Diarrhea
- Vomiting
- Abdominal pain
- Fat-soluble vitamin deficiency
- Elevated liver enzymes
Q: Can I take Livmarli with other medicines?
A: Yes, but if using bile acid-binding resins, separate administration by at least 4 hours.
Q: What is the storage guideline for Livmarli?
A: Store at 20–25°C (68–77°F). Discard the bottle 45 days after opening.
Q: Is it safe to buy Livmarli online in India?
A: Yes, Global Rare Meds ensures safe, legal, and verified sourcing of Livmarli for Indian and international patients through the Named Patient Program.
Contact Patient Support
If you have questions about your order, need assistance with documentation, or require support with medicine availability, our GlobalRareMeds Patient Support Team is here to help. We aim to respond within 24 hours, Monday to Friday, between 9:00 AM and 10:00 AM IST.
info@globalraremeds.com
Phone
+91 99675 15602
+91 99675 15602
Disclaimer
All trademarks, brands, and product names featured on this website are the property of their respective owners. GlobalRareMeds does not claim ownership or affiliation unless explicitly stated. Our role is to provide reliable and transparent access to difficult-to-source medicines through named-patient import services, based on valid prescriptions and legal requirements.
The product-related content on this website is shared to the best of our knowledge, compiled from publicly available sources and regulatory documents. However, GlobalRareMeds does not guarantee the accuracy, completeness, or timeliness of this information. We strongly recommend that all medical decisions, including usage and dosage, be made only in consultation with the prescribing doctor. GlobalRareMeds assumes no responsibility for consequences arising from reliance on this information without appropriate medical guidance
