- Home
- Products
Lonsurf (Trifluridine/Tipiracil)
Lonsurf (Trifluridine/Tipiracil)
- Medicine Name: LONSURF
- Generic Name: Trifluridine and Tipiracil
- Dosage Form & Strength:
- Tablets: 15 mg Trifluridine / 6.14 mg Tipiracil
- Tablets: 20 mg Trifluridine / 8.19 mg Tipiracil
- Tablets: 15 mg Trifluridine / 6.14 mg Tipiracil
- Manufactured By: Taiho Pharmaceutical Co., Ltd
Alternative Indian Generic Option:
- Brand Name: Tipanat
- Generic Name: Trifluridine and Tipiracil
- Manufactured By: Natco Pharma Ltd (India)
LONSURF is an oral chemotherapy medicine combining a nucleoside metabolic inhibitor (Trifluridine) and a thymidine phosphorylase inhibitor (Tipiracil). It is FDA-approved for use in:
- Metastatic Colorectal Cancer (mCRC):
For adult patients previously treated with fluoropyrimidine-, oxaliplatin-, irinotecan-based chemotherapy, anti-VEGF therapy, and, if RAS wild-type, anti-EGFR therapy. May be used alone or with bevacizumab. - Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma:
For patients treated with two or more chemotherapy lines, including fluoropyrimidine, platinum-based agents, and either a taxane or irinotecan. Applicable for those previously treated with HER2/neu-targeted therapy.
Recommended Dosage:
35 mg/m² (based on Trifluridine component) taken orally twice daily with food on Days 1–5 and Days 8–12 of each 28-day cycle. Maximum dose: 80 mg per administration.
Bone Marrow Suppression: May cause neutropenia, anemia, or thrombocytopenia. Monitor blood counts before and during treatment.
Pregnancy & Breastfeeding: LONSURF may cause fetal harm. Avoid during pregnancy and breastfeeding. Use effective contraception during treatment and for 6 months afterward.
Hepatic Impairment: Use with caution. Limited data available. Monitor liver function regularly.
Renal Impairment: Requires close monitoring and potential dose adjustments due to increased risk of toxicity.
To import LONSURF into India through Global Rare Meds, the following documentation is mandatory:
Required Documents:
- Valid prescription from a licensed doctor
- Diagnostic reports supporting the prescription
- Government-issued patient ID
- Import permit (if required by the destination country)
Availability in India:
Global Rare Meds helps legally import LONSURF across India, including Mumbai, Delhi, Hyderabad, Chennai, Ahmedabad, Bengaluru, Pune, Kolkata, Noida, and other cities.
Also available in:
SAARC countries (Afghanistan, Bangladesh, Bhutan, Maldives, Nepal, Pakistan, Sri Lanka) and Gulf countries (UAE, Oman, Qatar, Bahrain, Saudi Arabia, Kuwait).
📧 Email: info@globalraremeds.com
📞 Call / WhatsApp: +91-99675 15602
Global Rare Meds enables safe, legal access to LONSURF (Trifluridine and Tipiracil) and its generic Tipanat through:
- Verified sourcing from international manufacturers (USA, Canada, Europe, Australia)
- Prescription validation and pharmacist dispensing
- End-to-end handling, packaging, and delivery
- Centralized fulfillment from Ambernath, Thane District, India
- Exports available to countries where the product is not registered or is unavailable
Q1: What is the generic name of LONSURF?
A: Trifluridine and Tipiracil
Q2: Who manufactures LONSURF?
A: Manufactured by Taiho Pharmaceutical Co., Ltd
Q3: Is LONSURF approved by the FDA?
A: Yes, it was approved on September 22, 2015
Q4: What dosage forms are available?
A: Tablets containing either 15 mg / 6.14 mg or 20 mg / 8.19 mg (Trifluridine / Tipiracil)
Q5: What are the common side effects of LONSURF?
A:
- As monotherapy: Low blood counts, fatigue, nausea, diarrhea, vomiting, abdominal pain, fever
- With bevacizumab: Liver function changes, low sodium, decreased appetite
Q6: Is LONSURF available in India?
A: Yes, available via named-patient import through Global Rare Meds in all major Indian cities.
Q7: How much does LONSURF cost in India?
A: Pricing depends on international availability and exchange rates. For the latest pricing, contact +91-99675 15602 or email info@globalraremeds.com
Q8: What is Tipanat?
A: Tipanat is a generic version of LONSURF made by Natco Pharma Ltd, available in India and exportable worldwide.
Q9: Can Tipanat be exported?
A: Yes, Tipanat is exportable to Asia, Europe, the Middle East, and Africa under regulatory compliance and valid prescription.
Q10: How should LONSURF be stored?
A: Store at 20–25°C (68–77°F). Excursions permitted between 15–30°C (59–86°F).
Contact Patient Support
If you have questions about your order, need assistance with documentation, or require support with medicine availability, our GlobalRareMeds Patient Support Team is here to help. We aim to respond within 24 hours, Monday to Friday, between 9:00 AM and 10:00 AM IST.
info@globalraremeds.com
Phone
+91 99675 15602
+91 99675 15602
Disclaimer
All trademarks, brands, and product names featured on this website are the property of their respective owners. GlobalRareMeds does not claim ownership or affiliation unless explicitly stated. Our role is to provide reliable and transparent access to difficult-to-source medicines through named-patient import services, based on valid prescriptions and legal requirements.
The product-related content on this website is shared to the best of our knowledge, compiled from publicly available sources and regulatory documents. However, GlobalRareMeds does not guarantee the accuracy, completeness, or timeliness of this information. We strongly recommend that all medical decisions, including usage and dosage, be made only in consultation with the prescribing doctor. GlobalRareMeds assumes no responsibility for consequences arising from reliance on this information without appropriate medical guidance
