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Ayvakit (Avapritinib)
Ayvakit (Avapritinib)
Medicine Name: Ayvakit
Generic Name: Avapritinib
Dosage Form & Strength: Tablets – 25 mg, 50 mg, 100 mg, 200 mg, 300 mg
Manufactured By: Blueprint Medicines Corporation
Ayvakit is a kinase inhibitor approved for the treatment of:
- Gastrointestinal Stromal Tumor (GIST): For adults with unresectable or metastatic GIST with PDGFRA exon 18 mutations, including D842V
- Advanced Systemic Mastocytosis (AdvSM): Includes mast cell leukemia, aggressive SM, and SM-AHN (associated hematological neoplasm)
Recommended Dosage:
- GIST: 300 mg orally once daily
- AdvSM: 200 mg orally once daily
- Take on an empty stomach (≥1 hour before or ≥2 hours after meals)
- Do not retake if vomiting occurs; resume at next scheduled dose
- Avoid taking a missed dose if <8 hours remain until the next one
Intracranial Hemorrhage: Risk is higher in patients with thrombocytopenia or recent cerebrovascular events. Monitor carefully.
Platelet Count: Not recommended for AdvSM patients with platelet count <50 × 10⁹/L.
Cognitive Effects: May include memory loss or confusion. Temporarily withhold or reduce dosage based on severity.
Fetal Risk: Can cause harm to an unborn baby. Use effective contraception during treatment and for 6 weeks post-treatment.
Breastfeeding: Avoid during treatment and for 2 weeks after the final dose.
Documents Required to Import Ayvakit to India:
- Valid prescription from a qualified doctor
- Relevant diagnostic reports
- Government-issued photo ID of the patient
Order Confirmation:
Confirmed only upon receipt of valid prescription and import permit (if applicable)
Availability:
Available through Global Rare Meds in all major Indian cities, including Mumbai, Delhi, Chennai, Bangalore, Hyderabad, Kolkata, Ahmedabad, Pune and more. Also available for international export under the Named Patient Program.
To Order or Enquire Price:
- 📞 Call/WhatsApp: +91-99675 15602
- 📧 Email: info@globalraremeds.com
Global Rare Meds sources Ayvakit from certified suppliers in the USA, Canada, Europe, and Australia. Each order is:
- Dispensed only upon valid prescription
- Verified and packed by licensed pharmacists
- Dispatched securely from our Fulfillment Center in Ambernath, Thane District
- Shipped with full compliance to legal and safety standards
What is the generic name of Ayvakit®?
Avapritinib
Who manufactures Ayvakit®?
Blueprint Medicines Corporation
Is Ayvakit® FDA approved?
Yes, approved on January 9, 2020
What conditions does Ayvakit® treat?
GIST with PDGFRA exon 18 mutation and Advanced Systemic Mastocytosis (AdvSM)
What dosage forms are available?
Tablets: 25 mg, 50 mg, 100 mg, 200 mg, 300 mg
What are common side effects?
- GIST: cognitive issues, edema, nausea, fatigue, vomiting, diarrhea, appetite loss, dizziness
- AdvSM: diarrhea, nausea, edema, fatigue
What are the storage conditions?
Store at 20°C to 25°C (68°F to 77°F); excursions permitted 15°C to 30°C
Can I order Ayvakit® online from India?
Yes. Global Rare Meds facilitates legal procurement under the Named Patient Program
Contact Patient Support
If you have questions about your order, need assistance with documentation, or require support with medicine availability, our GlobalRareMeds Patient Support Team is here to help. We aim to respond within 24 hours, Monday to Friday, between 9:00 AM and 10:00 AM IST.
info@globalraremeds.com
Phone
+91 99675 15602
+91 99675 15602
Disclaimer
All trademarks, brands, and product names featured on this website are the property of their respective owners. GlobalRareMeds does not claim ownership or affiliation unless explicitly stated. Our role is to provide reliable and transparent access to difficult-to-source medicines through named-patient import services, based on valid prescriptions and legal requirements.
The product-related content on this website is shared to the best of our knowledge, compiled from publicly available sources and regulatory documents. However, GlobalRareMeds does not guarantee the accuracy, completeness, or timeliness of this information. We strongly recommend that all medical decisions, including usage and dosage, be made only in consultation with the prescribing doctor. GlobalRareMeds assumes no responsibility for consequences arising from reliance on this information without appropriate medical guidance
