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ERWINAZE (Asparaginase Erwinia Chrysanthemi)
ERWINAZE (Asparaginase Erwinia Chrysanthemi)
- Brand Name: Erwinaze
- Generic Name: Asparaginase Erwinia Chrysanthemi
- Dosage Form & Strength: 10,000 International Units (IU) lyophilized powder per single-dose vial
- Manufactured By: EUSA Pharma Inc.
- FDA Approval: November 2011
Erwinaze is a specialized asparagine-specific enzyme used in the treatment of acute lymphoblastic leukemia (ALL) in patients who have developed hypersensitivity to E. coli-derived asparaginase.
It is used as part of a multi-agent chemotherapy regimen in both pediatric and adult patients.
Mechanism of Action:
Erwinaze works by depleting asparagine, an amino acid essential for leukemia cell survival, thereby inhibiting their growth and promoting cell death.
Indication:
- Treatment of Acute Lymphoblastic Leukemia (ALL) in patients allergic or hypersensitive to native E. coli-based asparaginase preparations.
Recommended Dosage:
- Erwinaze is administered by intramuscular or intravenous injection, under supervision of a qualified oncologist.
- Dosing frequency is based on treatment protocol and body surface area.
- Dose modifications may be required in case of allergic reactions, pancreatitis, coagulopathy, or liver toxicity.
Hypersensitivity Reactions: Erwinaze may cause serious or fatal allergic reactions. Medical supervision and resuscitation equipment should be available during administration.
Pancreatitis: Discontinue treatment if clinical signs or laboratory evidence of pancreatitis develop.
Thrombosis and Hemorrhage: Monitor coagulation parameters and adjust therapy as required.
Hepatotoxicity: Liver enzyme elevations may occur. Regular liver function tests are advised.
Hyperglycemia and Diabetes: Monitor blood glucose levels in diabetic and non-diabetic patients.
Myelosuppression: Monitor complete blood counts during therapy.
Pregnancy Warning: May cause fetal harm. Effective contraception is advised for both men and women of reproductive age.
Documents Required for Import into India:
- Valid prescription from a licensed oncologist
- Patient’s diagnostic reports
- Government-issued photo ID of the patient
Order Confirmation:
Order will only be confirmed after submission of the above documents and any applicable import permit.
Availability in India
Erwinaze is not commercially available in India, but can be legally imported under the Named Patient Program (NPP) through GlobalRareMeds.com.
We provide support for secure and compliant access to Erwinaze in:
📍 Mumbai, Delhi, Kolkata, Hyderabad, Chennai, Bengaluru, Ahmedabad, Jaipur, Pune, Lucknow, and all other Tier I/II cities.
📦 Cold-chain packaging
📄 Verified by registered pharmacists
📬 Delivered via our Ambernath, Thane District Fulfillment Center
📞 Call/WhatsApp: +91-99675 15602
📧 Email: info@globalraremeds.com
GlobalRareMeds sources Erwinaze (Asparaginase Erwinia Chrysanthemi) from certified suppliers in the USA, Canada, and Europe.
We ensure:
- Cold-chain compliant delivery
- Regulatory import compliance
- Secure patient-level dispensing
Delivery is available pan-India and internationally, in compliance with medical and legal standards.
What is Erwinaze used for?
Erwinaze is used to treat Acute Lymphoblastic Leukemia (ALL) in patients who have developed hypersensitivity to E. coli-derived asparaginase.
Is Erwinaze FDA-approved?
Yes, it was approved by the U.S. FDA in November 2011.
How is Erwinaze administered?
Erwinaze is given via IV or IM injection, usually in a hospital or oncology center under medical supervision.
What are the common side effects of Erwinaze?
- Allergic reactions
- Pancreatitis
- Liver dysfunction
- Coagulopathies (clotting/bleeding disorders)
- Hyperglycemia
- Fatigue, fever, and nausea
Can Erwinaze be bought in India?
Yes, through the Named Patient Program, it can be imported legally for personal use with a valid prescription. GlobalRareMeds facilitates this process.
What is the price of Erwinaze in India?
Cost varies based on origin, availability, and shipping. For current pricing:
📞 +91-99675 15602 | 📧 info@globalraremeds.com
How should Erwinaze be stored?
Store the vial at 2°C to 8°C (refrigerated). Protect from light. Do not freeze.
Contact Patient Support
If you have questions about your order, need assistance with documentation, or require support with medicine availability, our GlobalRareMeds Patient Support Team is here to help. We aim to respond within 24 hours, Monday to Friday, between 9:00 AM and 10:00 AM IST.
info@globalraremeds.com
Phone
+91 99675 15602
+91 99675 15602
Disclaimer
All trademarks, brands, and product names featured on this website are the property of their respective owners. GlobalRareMeds does not claim ownership or affiliation unless explicitly stated. Our role is to provide reliable and transparent access to difficult-to-source medicines through named-patient import services, based on valid prescriptions and legal requirements.
The product-related content on this website is shared to the best of our knowledge, compiled from publicly available sources and regulatory documents. However, GlobalRareMeds does not guarantee the accuracy, completeness, or timeliness of this information. We strongly recommend that all medical decisions, including usage and dosage, be made only in consultation with the prescribing doctor. GlobalRareMeds assumes no responsibility for consequences arising from reliance on this information without appropriate medical guidance
