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PADCEV (Enfortumab Vedotin-ejfv)
PADCEV (Enfortumab Vedotin-ejfv)
- Medicine Name: PADCEV
- Generic Name: Enfortumab Vedotin-ejfv
- Dosage Form & Strength: Injection for IV Infusion – 20 mg and 30 mg vials
- Manufactured By: Astellas Pharma US, Inc.
PADCEV (Enfortumab Vedotin-ejfv) is a Nectin-4–targeted antibody-drug conjugate used in the treatment of locally advanced or metastatic urothelial cancer (mUC).
Approved indications include:
- Monotherapy: For adult patients with locally advanced or metastatic urothelial cancer who have been previously treated with both platinum-containing chemotherapy and a PD-1/PD-L1 inhibitor.
- Combination Therapy with Pembrolizumab: For adult patients with mUC who are ineligible for cisplatin-based chemotherapy.
Recommended Dosage:
- As a single agent: 1.25 mg/kg (max 125 mg) on Days 1, 8, and 15 of a 28-day cycle
- In combination with pembrolizumab: 1.25 mg/kg on Days 1 and 8 of a 21-day cycle
Treatment continues until disease progression or unacceptable toxicity.
Severe Cutaneous Reactions: Rare but serious cases of Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) have been reported. Monitor for skin changes.
Hyperglycemia & Diabetic Ketoacidosis: May occur even in non-diabetic patients. Monitor glucose levels closely.
Pneumonitis / Interstitial Lung Disease: Watch for symptoms like cough, breathlessness, or infiltrates on imaging.
Peripheral Neuropathy: Monitor for new or worsening neuropathy. Adjust or discontinue dosage as necessary.
Ocular Disorders & Extravasation Risk: Eye monitoring is advised. Ensure proper IV administration to avoid tissue injury.
PADCEV is not commercially available in India and must be imported on a named-patient basis. Global Rare Meds facilitates legal access under required medical guidelines.
Required Documentation:
- A valid prescription from a qualified medical practitioner
- Relevant diagnostic test reports
- Government-issued photo ID
- Import permit (if applicable)
Availability Across India:
PADCEV can be made available to doctors, hospitals, and patients in cities including Mumbai, Delhi, Noida, Gurgaon, Lucknow, Kolkata, Hyderabad, Chennai, Ahmedabad, Bengaluru, Pune, Jaipur, Chandigarh, and others.
Why Global Rare Meds:
- Legal access to globally approved medications
- Verified sourcing from USA, Canada, Europe, and Australia
- Transparent pricing and end-to-end patient support
- Fulfillment via our center in Ambernath, Thane District
📧 Email: info@globalraremeds.com
📞 Call / WhatsApp: +91-99675 15602
Global Rare Meds can assist in the international sourcing and delivery of PADCEV (Enfortumab Vedotin-ejfv):
- Sourced from authorized pharmaceutical distributors
- Prescriptions verified by licensed pharmacists
- Dispensed and securely shipped to the patient’s location
- Delivered directly via our fulfillment center in Ambernath, Thane District, India
- Global delivery supported in compliance with applicable health regulations
Q1: What is the generic name of PADCEV?
A: The generic name is Enfortumab Vedotin-ejfv.
Q2: Who manufactures PADCEV?
A: PADCEV is manufactured by Astellas Pharma US, Inc.
Q3: Is PADCEV FDA-approved?
A: Yes, PADCEV was approved by the U.S. FDA on December 18, 2019.
Q4: What are the available forms and strengths?
A: PADCEV is available as a lyophilized powder for intravenous infusion in 20 mg and 30 mg single-use vials.
Q5: How should PADCEV be stored?
A: Store in a refrigerator at 2°C to 8°C (36°F to 46°F) in its original carton. Do not freeze or shake.
Q6: Is PADCEV available in India?
A: PADCEV is not commonly stocked in pharmacies but can be imported legally with valid documentation. Global Rare Meds facilitates this process.
Q7: How do I order PADCEV?
A: Share a valid prescription, diagnostic reports, and ID proof with Global Rare Meds. If required, an import permit will be obtained.
Q8: Is it safe to purchase PADCEV online in India?
A: Yes, when sourced through legal, authorized facilitators like Global Rare Meds, which ensures compliance and product authenticity.
Contact Patient Support
If you have questions about your order, need assistance with documentation, or require support with medicine availability, our GlobalRareMeds Patient Support Team is here to help. We aim to respond within 24 hours, Monday to Friday, between 9:00 AM and 10:00 AM IST.
info@globalraremeds.com
Phone
+91 99675 15602
+91 99675 15602
Disclaimer
All trademarks, brands, and product names featured on this website are the property of their respective owners. GlobalRareMeds does not claim ownership or affiliation unless explicitly stated. Our role is to provide reliable and transparent access to difficult-to-source medicines through named-patient import services, based on valid prescriptions and legal requirements.
The product-related content on this website is shared to the best of our knowledge, compiled from publicly available sources and regulatory documents. However, GlobalRareMeds does not guarantee the accuracy, completeness, or timeliness of this information. We strongly recommend that all medical decisions, including usage and dosage, be made only in consultation with the prescribing doctor. GlobalRareMeds assumes no responsibility for consequences arising from reliance on this information without appropriate medical guidance
