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TEPADINA (Thiotepa)
TEPADINA (Thiotepa)
- Medicine Name: Tepadina
- Generic Name: Thiotepa
- Dosage Form & Strength: For injection – 15 mg and 100 mg, lyophilized white powder in a single-dose vial for reconstitution
- Manufactured By: Adienne SA
Tepadina (thiotepa for injection) is an alkylating agent used for multiple oncology and pre-transplant conditioning applications:
- Stem Cell Transplant in Pediatric Beta-Thalassemia: Administered with busulfan and cyclophosphamide to reduce the risk of rejection in children undergoing hematopoietic stem cell transplant (HSCT).
- Breast and Ovarian Cancer: Used in treating adenocarcinoma of the breast or ovaries, slowing cancer progression.
- Malignant Effusions: Controls fluid buildup in the lungs or abdomen due to metastasized cancers, improving comfort through intracavitary administration.
- Bladder Cancer (Superficial Papillary Carcinoma): Instilled directly into the bladder to eliminate cancerous cells on the bladder lining.
Recommended Dosage:
Pediatric HSCT Prep: 5 mg/kg IV twice, 12 hours apart on Day -6 before transplant.
Adenocarcinoma (Breast/Ovary): 0.3–0.4 mg/kg IV every 1 to 4 weeks; adjust weekly based on blood counts.
Malignant Effusions: 0.6–0.8 mg/kg administered via the same catheter used for fluid removal; repeat weekly as needed.
Bladder Cancer: 60 mg in 30–60 mL sodium chloride solution instilled via catheter, retained for 2 hours. Weekly for 4 weeks, with caution if
- Bone Marrow Suppression: May significantly reduce white blood cells, red blood cells, and platelets—requiring regular CBC monitoring.
- Allergic Reactions: Rash, itching, or breathing difficulty may indicate hypersensitivity—discontinue use if observed.
- Skin Toxicity: May cause redness, peeling, or rash. Report unusual skin symptoms promptly.
- Immunosuppression: Avoid live or attenuated vaccines during treatment due to reduced immune response.
- Liver Toxicity: Monitor liver function for signs of hepatic veno-occlusive disease or jaundice.
- Neurological Effects: May induce seizures, confusion, or tremors—report any neurological symptoms immediately.
- Secondary Cancers: Long-term use may increase risk of developing secondary malignancies.
- Pregnancy Warning: Tepadina can harm an unborn child. Use effective contraception during and after therapy as advised by your physician.
To Import Tepadina into India, the following documents are required:
- Prescription from a qualified oncologist
- Diagnostic reports
- Government-issued patient ID proof
Order Confirmation:
The order will only be processed upon receipt of valid documentation and import permit (if required).
Availability in India and Beyond:
Tepadina is not widely available in Indian retail pharmacies. GlobalRareMeds enables legal patient access under the Named Patient Import Program.
The medicine can be delivered to cities including Mumbai, Delhi, Hyderabad, Chennai, Bengaluru, Kolkata, Ahmedabad, and Pune. Availability also extends to Gulf countries and SAARC nations including Nepal, Sri Lanka, Bangladesh, Bhutan, and Maldives.
GlobalRareMeds sources Tepadina (Thiotepa) from certified global suppliers across the US, Canada, Europe, and Australia.
All prescriptions are processed and fulfilled via our Ambernath, Thane District-based fulfillment center, ensuring proper cold-chain logistics and compliance with import regulations. Delivery is facilitated across India and other approved countries.
For pricing, availability, or documentation assistance, contact us at:
📧 info@globalraremeds.com
📞 +91-99675 15602
📱 WhatsApp: +91-99675 15602
What is the generic name for Tepadina?
Thiotepa.
Who is the manufacturer of Tepadina?
Tepadina is manufactured by Adienne SA.
Is Tepadina FDA-approved?
Yes, Tepadina was approved by the FDA on January 26, 2017.
What is the form and strength of Tepadina?
Tepadina is available as a lyophilized powder for injection in 15 mg and 100 mg vials.
What are the common side effects of Tepadina?
Common side effects include anemia, neutropenia, thrombocytopenia, liver enzyme elevation, mucositis, CMV infection, hematuria, rash, and diarrhea.
Where can I get Tepadina in India at the best price?
You can legally import Tepadina in India through GlobalRareMeds with a valid prescription. Contact us for accurate pricing and availability.
Is Tepadina available in SAARC and Gulf countries?
Yes, we assist in supplying Tepadina to SAARC and Gulf regions, including Afghanistan, Bangladesh, UAE, Oman, and more.
Can I legally purchase Tepadina online in India?
Yes. With a valid prescription, you can legally procure Tepadina through GlobalRareMeds via our regulatory-compliant Named Patient Program.
What are the storage conditions for Tepadina?
Store between 2°C–8°C (36°F–46°F). Do not freeze. Protect from light and handle as per refrigeration guidelines.
Contact Patient Support
If you have questions about your order, need assistance with documentation, or require support with medicine availability, our GlobalRareMeds Patient Support Team is here to help. We aim to respond within 24 hours, Monday to Friday, between 9:00 AM and 10:00 AM IST.
info@globalraremeds.com
Phone
+91 99675 15602
+91 99675 15602
Disclaimer
All trademarks, brands, and product names featured on this website are the property of their respective owners. GlobalRareMeds does not claim ownership or affiliation unless explicitly stated. Our role is to provide reliable and transparent access to difficult-to-source medicines through named-patient import services, based on valid prescriptions and legal requirements.
The product-related content on this website is shared to the best of our knowledge, compiled from publicly available sources and regulatory documents. However, GlobalRareMeds does not guarantee the accuracy, completeness, or timeliness of this information. We strongly recommend that all medical decisions, including usage and dosage, be made only in consultation with the prescribing doctor. GlobalRareMeds assumes no responsibility for consequences arising from reliance on this information without appropriate medical guidance
