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ZELBORAF (Vemurafenib Tablet)
ZELBORAF (Vemurafenib Tablet)
- Medicine Name: Zelboraf
- API (Active Pharmaceutical Ingredient): Vemurafenib
- Dosage Form & Strength: Tablets: 240 mg
- Manufactured By: Roche and Plexxikon
Zelboraf (vemurafenib) is an oral targeted therapy used in the treatment of BRAF V600 mutation-positive conditions. It is primarily prescribed for adults with:
- Advanced or unresectable melanoma
- Erdheim-Chester Disease (ECD) with BRAF V600 mutation
Vemurafenib works by inhibiting certain abnormal forms of the BRAF protein, which drive cancer cell growth.
Recommended Dosage:
The standard dosage is 960 mg (four 240 mg tablets) taken orally every 12 hours, with or without food. Treatment should continue until disease progression or the emergence of intolerable side effects.
- Do not crush, chew, or split the tablets.
- If a dose is missed, it may be taken up to 4 hours before the next scheduled dose.
- If vomiting occurs, skip the dose and continue with the next scheduled one.
Secondary Malignancies: Vemurafenib increases the risk of developing new skin cancers, such as cutaneous squamous cell carcinoma. Monitor patients regularly for dermatologic changes.
Hypersensitivity: Severe allergic reactions may occur. Discontinue treatment if symptoms such as rash, fever, or swelling occur.
Serious Skin Reactions: Stevens-Johnson syndrome and other severe skin reactions have been reported. Discontinue therapy if severe rashes or blistering develop.
QT Prolongation: Vemurafenib may affect heart rhythm. Monitor ECG periodically and assess for signs like dizziness or fainting.
Ocular Toxicity: Eye inflammation and retinal disorders have been observed. Report any visual disturbances immediately.
Pregnancy Risk: This medication can cause fetal harm. Effective contraception must be used during treatment and for 2 weeks after the last dose.
Lactation: Breastfeeding is not advised during and for 2 weeks after the last dose of treatment, as effects on the infant are unknown.
Documents Required for Import to India:
- Valid prescription from an oncologist
- Patient’s diagnostic reports
- Government-issued patient ID proof
Order Confirmation:
Order will be confirmed upon submission of the required documents and import permit (if applicable).
GlobalRareMeds sources Zelboraf (vemurafenib) from certified suppliers in the USA, Canada, and Europe.
We ensure:
- 100% product authenticity
- Secure and compliant import process
- Availability across India in cities including Mumbai, Hyderabad, Delhi, Kolkata, Chennai, Ahmedabad, Bangalore, Pune, Jaipur, and more
- Orders dispatched directly from our fulfillment center in Ambernath, Thane District, following prescription verification
📞 Phone & WhatsApp: +91-99675 15602
📧 Email: info@globalraremeds.com
What is the generic name of Zelboraf?
Vemurafenib is the generic name for the brand Zelboraf.
Who manufactures Zelboraf?
Zelboraf is manufactured by Roche and Plexxikon.
Is Zelboraf approved by the FDA?
Yes. Zelboraf received FDA approval on August 17, 2011.
What dosage form is Zelboraf available in?
Zelboraf is available as 240 mg oral tablets.
What is Zelboraf used for?
Zelboraf is indicated for treating BRAF V600 mutation-positive unresectable or metastatic melanoma and Erdheim-Chester Disease.
What are the common side effects of Zelboraf?
- For melanoma: rash, joint pain, nausea, photosensitivity, fatigue, and skin papillomas
- For Erdheim-Chester Disease: rash, fatigue, alopecia, QT prolongation, and musculoskeletal pain
How much does Zelboraf cost in India?
To obtain the current price for Zelboraf 240 mg in India, contact GlobalRareMeds at +91-99675 15602 or email info@globalraremeds.com.
Can Zelboraf be shipped to other countries?
Yes. We can facilitate delivery to Gulf and SAARC countries including Afghanistan, Sri Lanka, Nepal, Bangladesh, Bhutan, and the Maldives, subject to legal import permissions.
Is it safe to purchase Zelboraf online from GlobalRareMeds?
Yes. GlobalRareMeds ensures legal and safe procurement through licensed global suppliers and dispatches medication only against a valid prescription.
What are the storage conditions for Zelboraf?
Store Zelboraf tablets at room temperature between 20–25°C. Keep in the original container with the lid tightly closed and protected from moisture.
Contact Patient Support
If you have questions about your order, need assistance with documentation, or require support with medicine availability, our GlobalRareMeds Patient Support Team is here to help. We aim to respond within 24 hours, Monday to Friday, between 9:00 AM and 10:00 AM IST.
info@globalraremeds.com
Phone
+91 99675 15602
+91 99675 15602
Disclaimer
All trademarks, brands, and product names featured on this website are the property of their respective owners. GlobalRareMeds does not claim ownership or affiliation unless explicitly stated. Our role is to provide reliable and transparent access to difficult-to-source medicines through named-patient import services, based on valid prescriptions and legal requirements.
The product-related content on this website is shared to the best of our knowledge, compiled from publicly available sources and regulatory documents. However, GlobalRareMeds does not guarantee the accuracy, completeness, or timeliness of this information. We strongly recommend that all medical decisions, including usage and dosage, be made only in consultation with the prescribing doctor. GlobalRareMeds assumes no responsibility for consequences arising from reliance on this information without appropriate medical guidance
